Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. We investigated whether the excess of adverse later effects in males operated through poorer neonatal profile or if there was an intrinsic male effect. Differences remained significant after adjusting for birth weight and gestation. At follow-up, disability, cognitive delay, and use of inhalers remained significant after further adjustment. We conclude that in very preterm infants, male sex is an important risk factor for poor neonatal outcome and poor neurological and respiratory outcome at follow-up.

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Sharon E. Oberfield, Aviva B. Sopher, Adrienne T. Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by premature adrenarche. Adrenarche is the maturation of the adrenal zona reticularis in both boys and girls, resulting in the development of pubic hair, axillary hair, and adult apocrine body odor.
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Development of sexuality is an integral part of the development and maturation of children. A range of sensational, emotional, and consequent sexual activities that may occur before or during early puberty , but before full sexual maturity is established. The development of child sexuality and the perception of child sexuality by adults is influenced by social and cultural aspects. The concept of child sexuality also played an important role in psychoanalysis. Until Sigmund Freud published his Three Essays on the Theory of Sexuality in , children were often regarded as asexual , having no sexuality until later development. Freud was one of the first researchers to seriously study child sexuality, and his acknowledgment of its existence was a significant change. Children are naturally curious about their bodies and sexual functions — they wonder where babies come from, they notice anatomical differences between males and females, and many engage in genital play or masturbation. Child sex play includes exhibiting or inspecting the genitals.
Although unprotected premature sexual activity is associated with well-defined biologic risks of sexually transmitted disease and pregnancy, the concomitant psychosocial risks are less well documented. The strength of association odds ratio of coital status with other risk behaviors and feelings was examined in junior high school students. The proportion of sexually experienced boys and girls increased with age. Nonvirginal boys and girls were significantly P less than. The odds ratios for nonvirginal youth ranged from 3. Nonvirginal boys and girls were also at significantly greater risk for engaging in minor delinquent acts and having school problems. Nonvirginal girls but not boys were 6.